What’s the Difference Between Botox, Dysport, Xeomin, and Daxxify?

When it comes to reducing fine lines and wrinkles, neuromodulators like Botox®, Dysport®, Xeomin®, and Daxxify™ are trusted solutions used by aesthetic professionals around the world. At Glamour Plastic Surgery and Med Spa, we specialize in tailoring these treatments to each patient’s unique facial anatomy, movement patterns, and aesthetic goals. While all four products are safe and effective, understanding their subtle differences can help you make an informed decision about which option may be best for you.

How Neuromodulators Work

All of these products are made from botulinum toxin type A, a purified protein that temporarily relaxes targeted facial muscles. These muscles are responsible for dynamic wrinkles – the ones that form from repeated expressions like frowning, squinting, or raising your eyebrows. By relaxing these muscles, neuromodulators smooth the skin above them, softening lines and preventing them from becoming deeper over time.

Importantly, these treatments do not “freeze” your face when administered properly. The goal is always to preserve natural expression while reducing the intensity of wrinkle-forming movement. This balance is what our team excels at – creating refreshed, subtle results that never look overdone.

While Botox, Dysport, Xeomin, and Daxxify all function in a similar way, their formulations, onset time, duration, and diffusion can vary. These differences allow us to customize your treatment to your skin type, muscle strength, and aesthetic preferences.

Botox® Cosmetic

As the most recognized name in aesthetic medicine, Botox has been a go-to for wrinkle reduction since its FDA approval in 2002. It has a long-standing track record for safety, efficacy, and consistent results.

Botox is commonly used to treat:

• Frown lines between the eyebrows (glabellar lines)
• Horizontal forehead lines
• Crow’s feet around the eyes
• Bunny lines on the nose
• Lip lines and downturned corners of the mouth
• Neck bands (platysmal bands)

Fast facts:

• Onset: 3 to 5 days
• Peak Results: 7 to 14 days
• Duration: 3 to 4 months
• Best For: Consistent, well-established results with broad treatment versatility

Dysport®

Dysport is structurally similar to Botox but features a slightly smaller molecule and a unique formulation. These differences allow it to spread more easily in the tissue, which is especially beneficial for treating larger areas like the forehead. Some patients also report a faster onset of results with Dysport.

This broader diffusion can result in smoother-looking outcomes for certain areas, though it requires an injector who understands how to work with the product precisely to avoid unwanted spread.

Fast facts:

• Onset: 2 to 3 days
• Peak Results: 5 to 7 days
• Duration: 3 to 4 months
• Best For: Patients looking for fast results and effective treatment across larger facial areas

Xeomin®

Xeomin stands out for its “naked” formulation – it contains only the active botulinum toxin molecule, without accessory proteins. This cleaner composition may reduce the risk of antibody formation in long-term users, which can potentially make treatments less effective over time.

Because of this, Xeomin is often favored by patients who have been using neuromodulators for many years or who may be sensitive to additives.

Fast facts:

• Onset: 3 to 5 days
• Peak Results: 7 to 10 days
• Duration: 3 to 4 months
• Best For: Patients interested in a pure formulation and potential long-term effectiveness

Daxxify™

Daxxify is the newest neuromodulator on the market, FDA-approved in 2022. What sets it apart is its unique peptide-based stabilizer, which allows for a longer duration of action – up to six months or more for many patients.

This longer-lasting effect means fewer visits per year, which is ideal for those with busy schedules or those who prefer less frequent maintenance. Daxxify is currently approved for frown lines, but it is being used off-label with great success in other areas.

Fast facts:

• Onset: 1 to 2 days
• Peak Results: 5 to 7 days
• Duration: 4 to 6+ months
• Best For: Patients looking for longer-lasting results and fewer annual treatments

Choosing the Right Neuromodulator

While all four options are highly effective, the best choice depends on several factors, including:

• Your treatment goals and desired longevity
• The areas being treated
• How quickly you want to see results
• Whether you have had previous experience with neuromodulators
• Your overall treatment plan, including skincare and other aesthetic procedures

At Glamour Plastic Surgery and Med Spa, Dr. Olga Bachilo and our expert injectors take the time to evaluate your facial anatomy, muscle strength, and skin condition to recommend the most appropriate product. We carry and administer Dysport, Xeomin, and Daxxify, and each product we offer is carefully selected for its proven results, safety profile, and patient satisfaction.

Our patient-centered approach ensures that your results are natural-looking, balanced, and long-lasting – whether you’re treating your forehead, eyes, or beyond.